Substituted 1-aryl-3-piperazin-1'-yl propanones

Details Substituted 1-aryl-3-piperazin-1'-yl propanones Substituted 1-aryl-3-piperazin-1'-yl propanones

1994-11-17

1997-12-02

Haley, Jacqueline

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

548248, A61K 31495, C07D41306

Patent

active

056938047

ABSTRACT:
Disclosed are compounds of formula I: ##STR1## wherein X is a carbonyl, sulfonyl, methylene, or methylene substituted with optionally substituted phenyl;

REFERENCES:
patent: 5338857 (1994-08-01), Ohto et al.
Natova et al. (1981), "Synthesis and Structures of Some Mannich Bases containing Five-Membered Heterocyles," God. Vissh. Khim.-Tekhnol. Inst. Sofia, vol. 24, No. 4, pp. 47-56.
Shi et al.(1987), "Synthesis of New Cerebral Vasodilator" Chemical Abstracts, vol. 106, No. 13, Abstract No 102232.b, p. 654.
Ohtaka et al. (1987), "Benzylpiperazine Derivatives. I., Syntheses and Biological Activites 1-(2,3,4-Trimethoxybenzyl)piperazine Derivatives" Chem. Pharm. Bull., vol. 35, No. 7, pp. 2774-2781.
Ohtaka et al. (1987), "Benzylpiperazine Derivatives. II., Syntheses and Cerebral Vasodilating Activities of Chem. Pharm. Bull., vol. 35, No. 7, pp. 2782-2791.
Vassileva et al. (1991), "Synthesis and Analgesic Activity of 1-Benzhydrilpiperazine Derivatives," Dokl. Bulg. Akad. Nauk., vol. 44, No. 12, pp. 37-39.
Database WPI, Week 8032, Derwent Publication Ltd., London, GB; AN 80-55940C and JP,A,55 083 772 (Kanebo K.K.) Jun. 25, (1980).

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