Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-03-01
2011-03-01
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S123000
Reexamination Certificate
active
07897612
ABSTRACT:
The invention described herein relates to certain bicyclic heteroaromatic N-substituted glycine derivatives of formula (I)which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
REFERENCES:
Jordan, V. C. Nature Reviews: Drug Discovery, 2, 2003, 205.
Dörwald, F. Zaragoza. Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design, Weinheim: WILEY-VCH Verlag GmbH & Co. KGaA, 2005, Preface.
Hsieh, et al. Chronic intermittent administration of HIF prolyl hydroxylase inhibitor significantly induces erythropoietin and increases total hemoglobin in normal rhesus macaques. Blood, Nov. 16, 2005, vol. 106, No. 11, Part 1, abstract p. 169A, see entire abstract.
Colón Mariela
Fitch Duke M.
Gimmi Edward R.
GlaxoSmithKline LLC
Kinzig Charles M.
Peng Tony W.
Willis Douglas M
LandOfFree
Substituted 1,8-naphthyridinecarboxamides for use as prolyl... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted 1,8-naphthyridinecarboxamides for use as prolyl..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 1,8-naphthyridinecarboxamides for use as prolyl... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2724536