Substituted 1,8-dihydroxy-9-(10H)anthracenones

Details Substituted 1,8-dihydroxy-9-(10H)anthracenones Substituted 1,8-dihydroxy-9-(10H)anthracenones

1981-01-08

1982-04-27

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

260351, A61K 3112, C07C 5034

Patent

active

043271146

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be identical to or different from each other, are each hydrogen, halogen, branched alkyl of 3 to 12 carbon atoms or cycloalkyl of 3 to 12 carbon atoms, provided, however, that at least one of R.sub.1 to R.sub.4 is other than hydrogen; the compounds are useful as dermatologics for the treatment of psoriasis, dandruff, ichthyosis and hyperkeratotic skin conditions.

REFERENCES:
patent: 2929825 (1960-03-01), Stephens
patent: 3515731 (1970-06-01), Conover
patent: 3538126 (1970-11-01), Lange et al.
patent: 3947594 (1976-03-01), Randall
patent: 4007271 (1977-02-01), Robertson
Mustakallia, Acta Dermatovener, vol. 59, #85, p. 125, (1979).

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