Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-10-07
2008-08-12
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S360000, C544S364000
Reexamination Certificate
active
07410970
ABSTRACT:
The invention concerns substituted 1,4-di-piperidin-4-yl-piperazine derivatives having neurokinin antagonistic activity, in particular NK1antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment of emesis, anxiety, depression, pain, pancreatitis and IBS.
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patent: 2006/0252747 (2006-11-01), Janssens et al.
patent: WO 97/16440 (1997-05-01), None
Smith et al. March's Advanced Organic Chemistry, 2001, 681-690.
Jantzen and Robinson, Modern Pharmaceutics (editor Gilbert Banker), 1996, pp. 451 and 596.
Giuseppe et al. Expert Opinion on Therapeutic Patents, 1997, 307-323.
International Search Report for PCT/EP03/50697 date Feb. 10, 2004.
De Boeck Benoît Christian Albert Ghislain
Diels Gaston Stanislas Marcella
Janssens Frans Eduard
Leenaerts Joseph Elisabeth
Sommen François Maria
Janssen Pharmaceutica N.V.
Jarrell Noble
Wilson James O.
woodcock Washburn LLP
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