Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-12-05
2006-12-05
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S267000, C544S251000
Reexamination Certificate
active
07144887
ABSTRACT:
The present invention provides a compound of formula (I) in which R1is generally hydrogen or CF3, R2is generally hydrogen, W is a cyclic amine, a heterocycle or a group L-Y—X where L-Y is a linking portion and X is generally an aromatic or non-aromatic heterocycle, alkyl or alkylcarbonyl and Z is generally a heterocycle such as 5-methylisoxazol-3-yl, and pharmaceutically acceptable salts thereof for enhancing cognition in conditions such as Alzheimer's Disease, pharmaceutical compositions comprising them, their use for manufacturing medicaments and methods of treatment using them
REFERENCES:
patent: 4788186 (1988-11-01), Occelli et al.
patent: 5306819 (1994-04-01), Albaugh et al.
patent: 6337331 (2002-01-01), Broughton et al.
patent: 6730681 (2004-05-01), Chambers et al.
patent: 19617862 (1997-10-01), None
patent: WO 98/04559 (1998-02-01), None
patent: WO 98/50385 (1998-11-01), None
patent: 99/65907 (1999-12-01), None
G. Tarzia et al.: Benzodiazepine receptor ligand. Farmaco Ed. Sci. vol. 43, No. 2, 1988, pp. 189-201.
T.C. Porter et al.: “Tetrazolo [1,5-a]quinolines . . . ” SYNTHESIS, No. 7, 1997, pp. 773-777.
G. Biagi et al.: “1,2,3-Triazolo[1,5-a]quinazolines . . . ” FARMACO, vol. 51, No. 2, 1996, pp. 131-136.
L. Bertelli et al.: “Substituted 1,2,3-triazolo[2,5-a]quinazolines . . . ” Eur. J. Med. Chem., vol. 35, 2000, pp. 333-341.
Bryant Helen Jane
Chambers Mark Stuart
Jones Philip
MacLeod Angus Murray
Maxey Robert James
Merck Sharp & Dohme Ltd.
Todaro John C.
Truong Tamthom N.
Wilson James O.
Winokur Melvin
LandOfFree
Substituted 1,2,3-triazolo[1,5-a]quinazolines for enhancing... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted 1,2,3-triazolo[1,5-a]quinazolines for enhancing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 1,2,3-triazolo[1,5-a]quinazolines for enhancing... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3660871