Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1996-05-07
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514212, 5142328, 514253, 514307, 514323, 540602, 544142, 544372, 546147, 546200, 548439, A61K 3140, C07D20994
Patent
active
055147003
ABSTRACT:
There are disclosed various compounds of the formula below, ##STR1## where n, X and R.sub.1 through R.sub.4 are as defined in the specification, which are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease.
Compounds of this invention also inhibit monoamine oxidase and/or act at central .alpha..sub.2 -adrenergic receptors, and hence are useful as antidepressants.
REFERENCES:
patent: 3514462 (1970-05-01), Hester, Jr.
Merriman Michael C.
O'Malley Gerard J.
Ong Helen H.
Palermo Mark G.
Hoechst-Roussel Pharmaceuticals Incorporated
Maurer Barbara V.
Ramsuer Robert W.
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