Substantially pure steroidogenesis inducing protein and uses the

Details Substantially pure steroidogenesis inducing protein and uses the Substantially pure steroidogenesis inducing protein and uses the

1991-05-30

1996-01-16

Warden, Jill

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 530324, 435268, A01N 3718, A61K 3800, C07K 500, C07K 1700

Patent

active

054847672

ABSTRACT:
A substantially pure steroidogenesis inducing protein ("SIP") is disclosed. The protein is characterized by a molecular weight of 60 kd as determined by SDS-PAGE, a pI of 4.7 to 4.9 and a non cAMP linked mechanism of action. The protein stimulates production of sex and adrenal cells, and also stimulates the production of various steroid hormones. The use of the pure protein in various therapeutic contexts as well as pharmaceutical compositions for therapy are also disclosed.

REFERENCES:
patent: 4196123 (1980-03-01), Rosemberg
patent: 4945055 (1990-07-01), Kuehl et al.
Berne et al Physiology (CV Mosby Co. 2nd ed. 1988) 986-997, 1017-1018.
Khan et al., Acta Endocrinologica (1988) vol. 118 283-293.

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