Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Reexamination Certificate
2006-06-20
2006-06-20
Weber, Jon (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
C530S356000
Reexamination Certificate
active
07064187
ABSTRACT:
The invention provides an article of manufacture comprising a substantially non-immunogenic injectable collagen for implantation into humans. The invention further provides methods for preparing injectable collagen material by removing collagen-containing material from a non-human animal; washing in saline and alcohol; subjecting material to cellular disruption treatment; and digesting the material with a proteoglycan-depleting factor and/or glycosidase and optionally following with a capping treatment. The invention also provides an article of manufacture produced by the method. The injectable collagen material of the invention are substantially non-immunogenic and have substantially the same mechanical properties as a corresponding native soft tissue.
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Associates in Otolarynology. The Science of Collagen. www.entdr.com/collagen.html.
Spira et al. Human amnion collagen for soft tissue augementation—biochemical characterizations and animal observations. Journal of Biochemical Materials Research. 1994. vol. 28, No. 1, pp. 91-96.
Copy of International Search for PCT/US03/37769.
CrossCart, Inc.
Greenberg & Traurig, LLP
Lappin Mark G.
Noakes Suzanne M.
Weber Jon
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