Substances with heparin-like structure and their method of produ

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 54, 536124, C07H 100, C08B 3710

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active

053409329

ABSTRACT:
A process for the synthesis of a new N-acetylated Heparin derivative is disclosed which includes a reaction of a N-desulfated Heparin with acetic anhydride. The new compound so obtained and pharmaceutical compositions containing it, exhibit antithrombotic and fibrinolytic properties with low anticoagulant activity.

REFERENCES:
patent: 3033750 (1962-05-01), Velluz
patent: 4489066 (1984-12-01), Fedeli
patent: 4692435 (1987-09-01), Lormeau et al.
patent: 4727063 (1988-02-01), Naggi et al.
patent: 4816446 (1989-03-01), Feller et al.
patent: 4882318 (1989-11-01), Vlodavsky et al.
patent: 5013724 (1991-05-01), Petitou et al.
patent: 5032679 (1991-07-01), Brandley et al.
Danishefsky et al.; Arch. Biochem. Biophys. 90:114-121 (1960).
Nagasawa et al; J. Biochem. 81:989-993 (1977).
Hook et al; Analytical Biochemistry 119:236-245 (1982).
Nagasawa et al; Carbohydrate Research 111:273-281 (1983).
Ayotte et al; Carbohydrate Research 145:267-277 (1986).
Irimura et al; Biochemistry 25(18):5322-5328 (1986).

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