Substance P-Saporin (SP-SAP) conjugates and methods of use there

Details Substance P-Saporin (SP-SAP) conjugates and methods of use there Substance P-Saporin (SP-SAP) conjugates and methods of use there

1997-07-09

2000-05-16

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 530320, 530350, A61K 3800, A61K 3816

Patent

active

060637587

ABSTRACT:
This invention provides a conjugate comprising Substance P, and analogs thereof, and Saporin. This invention provides a method of reducing the perception of pain by a subject comprising administering to the subject an effective dose of the pharmaceutical composition of the conjugate comprising Substance P, and analogs thereof, and Saporin, so as to reduce the perception of pain by the subject. This invention provides a method of selectively destroying NK-1 receptor expressing cells in a subject comprising administering to the subject an effective dose of the conjugate comprising Substance P, and analogs thereof, and Saporin so as to selectively destroy NK-1 receptor expressing cells. Lastly, this invention provides a method for treating a NK-1 receptor associated disorder in a subject, which comprises administering to the subject an amount of the pharmaceutical composition comprising Substance P, and analogs thereof, and Saporin thereby treating the disorder associated with the NK-1 receptor.

REFERENCES:
patent: 5191067 (1993-03-01), Lappi et al.
patent: 5679637 (1997-10-01), Lappi et al.

Affiliated with

Also associated with

Rating

Substance P-Saporin (SP-SAP) conjugates and methods of use there does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substance P-Saporin (SP-SAP) conjugates and methods of use there, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substance P-Saporin (SP-SAP) conjugates and methods of use there will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-258923