Substance K-259-2 and a process for producing the same

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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435169, A61K 3574, C12P 106

Patent

active

046923101

ABSTRACT:
A new substance K-259-2 having a molecular formula of C.sub.21 H.sub.18 O.sub.7, a molecular weight of 382 and an elemental analysis (%) of H: 4.50, C: 65.53 and N: 0. This substance is of interest in providing a new vasodilating agent in view of its ability to dilate the blood vessel, particularly the artery, of mammals. This substance may be obtained by fermentation of a microorganism Micromonospora sp. K-259 (FERM BP 569).

REFERENCES:
Tawaka et al., J of Antibiotics, vol. XXXV, No. 2, pp. 151-156, (Feb. 1982).
Yoshida et al., J of Antibiotics, vol. XXXV, No. 2, pp. 157-163, (Feb. 1982).

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