Substance-conjugated complement component C1q

Details Substance-conjugated complement component C1q Substance-conjugated complement component C1q

1987-03-30

1989-11-21

Rosen, Sam

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

435 4, 435 14, 435 21, 435 26, 435 28, 435 7, 514 2, 514 3, 514 6, 530350, 530404, 530408, C07K 1500

Patent

active

048824232

ABSTRACT:
A substance-conjugated complement component Clq is provided. A substance such as signal emitting substances or cell function regulating substances is conjugated via a sulfur atom to at least one site of the component. The site is not involved in binding immunoglobulins. A marker-labelled complement component Clq is used for measuring a complement-binding antibody, an antigen, a neutralizing antibody or a substance produced internally of and at the surface of a cell or a microorganism by measuring the marker.

REFERENCES:
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Nishioka et al.--Chem. Abst. vol. 97 (1982) p. 196,644h.
Bing et al.--Chem. Abst. vol. 97 (1982) p. 53755j.
Ingham et al.--Chem. Abst. vol. 98 (1983) p. 177,328n.

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