Subfamily of RNA helicases which are modulators of the...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...

Reexamination Certificate

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C435S004000, C435S015000, C435S193000, C536S023100, C536S023200, C530S350000

Reexamination Certificate

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06989256

ABSTRACT:
An isolated multiprotein complex ofS. cerevisiaecomponents is provided that is effective to modulate peptidyl transferase activity during translation. This complex includes a Modulator of Translation Termination protein (Mtt1p, also referred to as helicase B), a Upf1 protein, a peptidyl eukaryotic release factor 1 (eRF1) and a peptidyl eukaryotic release factor 3 (eRF3).

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