Subcutaneous analyte sensor

Details Subcutaneous analyte sensor Subcutaneous analyte sensor

2005-10-04

2005-10-04

Robinson, Daniel (Department: 3742)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C356S478000

Reexamination Certificate

active

06952603

ABSTRACT:
Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantable optical-sensing element that comprises a body, and a membrane mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable to the analyte, but is impermeable to background species in the biological matrix. A refractive element is positioned in the cavity. A light source transmits light of a first intensity onto the refractive element, and a light detector receives light of a second intensity that is reflected from the cavity. A controller device optically coupled to the detector compares the first and second light intensities, and relates the intensities to analyte concentration.

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