Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1995-03-30
1997-08-26
Barts, Samuel
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
554224, A61K 3120
Patent
active
056611803
ABSTRACT:
There is disclosed structured lipid containing either a gamma-linolenic acid or a dihomogamma-linolenic acid residue, together with an n-3 fatty acid residue and a medium chain fatty acid residue on the same glycerol backbone. This structured lipid is particularly well adapted to the treatment of disease or stress states. The gamma-linolenic or dihomogamma-linolenic acid residues modify the prostanoid synthesis pathway, reducing the level of series "2" prostanoids and elevating the levels of series "1" and "3" prostanoids. The n-3 fatty acid residue enhances the level of series "1" prostanoids as well as increases the production of series "3" prostanoids. The medium chain fatty acid residues enhances the absorption of the structured lipid. There is also disclosed enteral and parenteral diets as well as nutritional supplements containing the structured lipids of the invention.
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Bistrian Bruce Ryan
DeMichele Stephen Joseph
Karlstad Michael Donald
Mascioli Edward Anthony
Abbott Laboratories
Barts Samuel
Brainard T. D.
Drayer L. R.
New England Deaconess Hospital
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