Structured bioerodible drug delivery device

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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128260, 424 14, 424 16, 424 20, 424 21, 424 22, A61K 922, A61K 950, A61K 952, A61K 954

Patent

active

039624145

ABSTRACT:
A drug delivery device for the continuous and controlled administration of a predetermined therapeutically effective dosage of eye drug to the eye of a mamallian patient over a prolonged period of time. The device meters the flow of polylactic acid polymer micro-encapsulated eye drug by means of a drug release rate controlling material comprised of an anionic polyvalent metal cation cross-linked polyelectrolyte. The device bioerodes in the biological environment of the patient concurrently with the dispensing or at a point in time after the dispensing of the therapeutically desired amount of drug.

REFERENCES:
patent: 3640741 (1972-02-01), Etes
patent: 3755558 (1973-08-01), Scribner
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3826258 (1974-07-01), Abraham

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