Structure for introducing a plurality of solutions, micro...

Chemistry: analytical and immunological testing – Including sample preparation – Volumetric liquid transfer

Reexamination Certificate

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C436S043000, C436S063000, C436S086000, C436S174000, C436S178000, C436S179000, C422S050000, C422S051000, C422S068100, C422S081000, C422S082000, C422S105000, C422S105000

Reexamination Certificate

active

07910380

ABSTRACT:
The present invention relates to a structure (a solution introducing structure) for introducing a plurality of solutions (a sample and/or a reagent solution) in highly accurate volume, in high amount and simply, into a channel, in particular a channel of a micro fluidic device, a micro fluidic device having said structure, a method for introducing a solution using said device, a method for separation of a substance, and a method for separating a complex between an analyte or analogue thereof, and a substance binding to said analyte or analogue thereof (hereinafter may be abbreviated as a complex forming substance or CFS) which is obtained by reacting a plurality of solutions introduced by these, and said CFS or analogue not involved in formation of said complex, rapidly, simply and in high accuracy, along with a method for measuring an analyte or an analogue thereof in a sample in high sensitivity.

REFERENCES:
patent: 5869004 (1999-02-01), Parce et al.
patent: 6403338 (2002-06-01), Knapp et al.
patent: 7378280 (2008-05-01), Quake et al.
patent: 2002/0076806 (2002-06-01), Van Gelder
patent: 2006/0191792 (2006-08-01), Herr et al.
patent: 2008/0254997 (2008-10-01), Oku et al.
patent: WO 01/59440 (2001-08-01), None
Effenhauser et al., “Glass Chips for High-Speed Capillary Electrpphoresis Separations with Submicrometer Plate Heights,” Analytical Chemistry, Oct. 1, 1993, 65(19):2637-2642.

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