Structure determining method of functional substance having...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S023100, C536S025300, C536S026600, C435S091100

Reexamination Certificate

active

07951533

ABSTRACT:
Novel technologies are provided to determine the structure of and produce a functional substance that has a high affinity to a target. Candidates for a substance having an affinity to a target (functional substance) are synthesized; a functional substance that has an affinity to the target is selected from among the functional substance candidates; a specific substituent group is eliminated from the selected functional substance; the functional substance from which the specific substituent group has been eliminated is amplified; the structure of the amplified functional substance is determined; and the functional substance is produced, based on the structure.

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Anna V. Kachalova et al., “Synthesis of Modified Nucleotide Building Blocks Containing Electrophilic Groups in the 2′-Position”,Nucleosides, Nucleotides&Nucleic Acids, vol. 19, No. 10-12, 2000, p. 1693-1707.

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