Structure based designed herbicide resistant products

Details Structure based designed herbicide resistant products Structure based designed herbicide resistant products

1995-04-20

1998-12-29

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 6, 435 29, 435232, 435252, 43525233, 4353201, 536 232, C12Q 100

Patent

active

058539735

ABSTRACT:
Disclosed herein are structure-based modelling methods for the preparation of acetohydroxy acid synthase (AHAS) variants, including those that exhibit selectively increased resistance to herbicides such as imidazoline herbicides and AHAS inhibiting herbicides. The invention encompasses isolated DNAs encoding such variants, vectors that include the DNAs, and methods for producing the variant polypeptides and herbicide resistant plants containing specific AHAS gene mutations. Methods for weed control in crops are also provided.

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