Structurally defined oligomers and preparation thereof for the p

Details Structurally defined oligomers and preparation thereof for the p Structurally defined oligomers and preparation thereof for the p

1985-08-23

1989-05-23

Genstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562500, 562503, C07C17700

Patent

active

048332712

ABSTRACT:
Structurally-defined, low molecular weight oligomers and preparation thereof which are active in the protection of oxidative physphorylation of mitochondria and exhibit ionophoretic activity. Said structurally defined low molecular weight oligomers are synthesized using a modified 15-dehydro PGB.sub.1 such as 16,16-dimethyl-15-dehydro prostaglandin B.sub.1 as a precursor to obtain oligomeric mixtures which are structurally defined and active in the protection of oxidative phosphorylation and exhibit ionophoretic activity. Synthesis of modified 15-dehydro-PGB.sub.1 ; 16,16-dimethyl-15-dehydro-prostagalandin B.sub.1 ; is also described.

REFERENCES:
patent: 4153808 (1979-05-01), Polis

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