Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-12-05
2006-12-05
Solola, Taofiq (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07145025
ABSTRACT:
A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a subject is administered a carotenoid structural analog, either alone or in combination with another carotenoid analog, or co-antioxidant formulation. The analog or analog combination is administered such that the subject's risk of experiencing diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals may be thereby reduced. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of ischemia-reperfusion injury, liver disease, cancer, cardiac arrhythmia and/or sudden cardiac death, and/or any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In one embodiment, a water-soluble and/or water-dispersible astaxanthin analog is particularly effective. This invention further includes pharmaceutical compositions comprising structural carotenoid analogs either alone or in combination.
REFERENCES:
patent: 3354218 (1967-11-01), Surmatis
patent: 3755422 (1973-08-01), Morel
patent: 3965261 (1976-06-01), Gainer
patent: 3975519 (1976-08-01), Gainer
patent: 3989757 (1976-11-01), Surmatis
patent: 4009270 (1977-02-01), Gainer
patent: 4038144 (1977-07-01), Gainer
patent: 4046880 (1977-09-01), Gainer
patent: 4070460 (1978-01-01), Gainer
patent: 4176179 (1979-11-01), Gainer
patent: 4304784 (1981-12-01), Fujimura et al.
patent: 4435427 (1984-03-01), Hoppe et al.
patent: 4491574 (1985-01-01), Seifter et al.
patent: 5057494 (1991-10-01), Sheffield
patent: 5153001 (1992-10-01), Ismail
patent: 5221668 (1993-06-01), Henninfield et al.
patent: 5278189 (1994-01-01), Rath et al.
patent: 5310554 (1994-05-01), Haigh
patent: 5326757 (1994-07-01), Demopoulos
patent: 5328845 (1994-07-01), Finkelstein et al.
patent: 5346488 (1994-09-01), Prince et al.
patent: 5364563 (1994-11-01), Cathrein et al.
patent: 5422247 (1995-06-01), Finkelstein et al.
patent: 5455362 (1995-10-01), Ernst et al.
patent: 5457135 (1995-10-01), Baranowitz et al.
patent: 5492701 (1996-02-01), Cervos et al.
patent: 5527533 (1996-06-01), Tso et al.
patent: 5536504 (1996-07-01), Eugster et al.
patent: 5589468 (1996-12-01), Lin et al.
patent: 5607707 (1997-03-01), Ford et al.
patent: 5607839 (1997-03-01), Tsubokura et al.
patent: 5612485 (1997-03-01), Schlipalius
patent: 5643943 (1997-07-01), Gamache et al.
patent: 5668183 (1997-09-01), Leuenberger
patent: 5705180 (1998-01-01), Schlipalius
patent: 5744502 (1998-04-01), Lignell et al.
patent: 5773026 (1998-06-01), Schlipalius
patent: 5801159 (1998-09-01), Miller et al.
patent: 5811446 (1998-09-01), Thomas
patent: 5837224 (1998-11-01), Voorhees et al.
patent: 5849345 (1998-12-01), Giger et al.
patent: 5854015 (1998-12-01), Garnett et al.
patent: 5858700 (1999-01-01), Ausich et al.
patent: 5863953 (1999-01-01), Luddecke et al.
patent: 5871766 (1999-02-01), Hennekens
patent: 5876782 (1999-03-01), Sas et al.
patent: 5886053 (1999-03-01), Schmutzler et al.
patent: 5891907 (1999-04-01), Kolter et al.
patent: 5895659 (1999-04-01), Luddecke et al.
patent: 5897871 (1999-04-01), Schlipalius
patent: 5925684 (1999-07-01), Schweikert et al.
patent: 5959138 (1999-09-01), Torres-Cardona et al.
patent: 5968251 (1999-10-01), Auweter et al.
patent: 5976575 (1999-11-01), Gellenbeck
patent: 6020003 (2000-02-01), Stroh et al.
patent: 6040147 (2000-03-01), Ridker et al.
patent: 6043259 (2000-03-01), Dhalla et al.
patent: 6046181 (2000-04-01), Oonishi et al.
patent: 6051587 (2000-04-01), Dakashinamurti et al.
patent: 6054491 (2000-04-01), Lignell et al.
patent: 6060511 (2000-05-01), Gainer
patent: 6075058 (2000-06-01), Handelman
patent: 6083520 (2000-07-01), Toneby
patent: 6093348 (2000-07-01), Kowalski et al.
patent: 6132790 (2000-10-01), Schlipalius
patent: 6218436 (2001-04-01), Howard et al.
patent: 6232060 (2001-05-01), Miller et al.
patent: 6245818 (2001-06-01), Lignell
patent: 6258855 (2001-07-01), Lorenz et al.
patent: 6265450 (2001-07-01), Asami et al.
patent: 6313169 (2001-11-01), Bowen et al.
patent: 6331537 (2001-12-01), Hamilton et al.
patent: 6335015 (2002-01-01), Lignell et al.
patent: 6344214 (2002-02-01), Lorenz
patent: 6399105 (2002-06-01), Collin
patent: 6426362 (2002-07-01), Miller et al.
patent: 6428816 (2002-08-01), Schlipalius et al.
patent: 6540654 (2003-04-01), Levy et al.
patent: 6541519 (2003-04-01), Collin et al.
patent: 6579544 (2003-06-01), Rosenberg et al.
patent: 2002/0110604 (2002-08-01), Babish et al.
patent: 2003/0035821 (2003-02-01), Heaton et al.
patent: 2003/0180406 (2003-09-01), Sies
patent: 2005/0004235 (2005-01-01), Lockwood et al.
patent: 2005/0009758 (2005-01-01), Lockwood et al.
patent: 2005/0009788 (2005-01-01), Lockwood et al.
patent: 2005/0009930 (2005-01-01), Lockwood et al.
patent: 2005/0026874 (2005-02-01), Lockwood et al.
patent: 2005/0037995 (2005-02-01), Lockwood et al.
patent: 2005/0049248 (2005-03-01), Lockwood et al.
patent: 2005/0059635 (2005-03-01), Lockwood et al.
patent: 2005/0059659 (2005-03-01), Lockwood et al.
patent: 2005/0065096 (2005-03-01), Lockwood et al.
patent: 2005/0065097 (2005-03-01), Lockwood et al.
patent: 2005/0075316 (2005-04-01), Lockwood et al.
patent: 2005/0075337 (2005-04-01), Lockwood et al.
patent: 2005/0090469 (2005-04-01), Lockwood et al.
patent: 2005/0113372 (2005-05-01), Lockwood et al.
patent: 2005/0143475 (2005-06-01), Lockwood et al.
patent: 2005/0148517 (2005-07-01), Lockwood et al.
patent: 2005/0261254 (2005-11-01), Lockwood et al.
patent: 0204987 (1986-12-01), None
patent: 07300421 (1995-11-01), None
patent: 08073312 (1996-03-01), None
patent: 08337592 (1996-12-01), None
patent: 09084591 (1997-03-01), None
patent: 09202730 (1997-08-01), None
patent: 10155459 (1998-06-01), None
patent: 10327865 (1998-12-01), None
patent: 2001114673 (2001-04-01), None
patent: WO 90/10440 (1990-09-01), None
patent: WO 92/05780 (1992-04-01), None
patent: WO 98/29111 (1998-07-01), None
patent: WO 98/37874 (1998-09-01), None
patent: WO 99/11251 (1999-03-01), None
patent: WO 99/30701 (1999-06-01), None
patent: WO 02/47680 (2002-06-01), None
patent: WO 02/068385 (2002-09-01), None
patent: WO 03/066583 (2003-08-01), None
Deli et al., Carotenod 5,6-and 3,6-epoxide., ARKIVOC, vol. 2004 part (vii), www.arkat-usa.org/ark/journal/2004.
Buchwald, M. and W.P. Jencks, “Optical properties of astaxanthin solutions and aggregates.”Biochemistry1968, 7: \834-843.
Reznikoff et al “Quantitative and Qualitative Studies of Chemical Transformation of Cloned C3H Mouse Embryo Cells Sensitive to Postconfluence Inhibition of Cell Division.”Cancer Research, 1973, 33:2339-2349.
Andrewes et al. “Animal carotenoids. 9. On the absolute configuration of astaxanthin and actinioerythrin.”Acta Chem. Scand. 1974, B28:730-736.
Salares et al. “Resonance Raman spectra of lobster shell carotenoproteins and a model astaxanthin aggregate. A possible photobiological function for the yellow protein.”Biochemistry1977,16:4751-4756.
Salares et al. Excited state (exciton) interactions in polyene aggregates.J. Raman Spectr. 1977, 6:282-288.
Halliwell, B. “Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates. Is it a mechanism for hydroxyl radical production in biological systems?”FEBS Lett1978, 92:321-326.
Harada et al. “Circular dichroic power due to chiral exciton coupling between two polyacene chromophores.”J. Am. Chem. Soc. 1978, 100:4029-4036.
Stuber et al. “A new synthesis of L-threo-hex-2-enaro-1,4-lactone (“saccharoascorbic” acid): a method for the protection of the encdiol of ascorbic acid.”Carb. Res. 1978, 60:251-258.
Bock et al. “Preparation of some bromodeoxyaldonic acids.”Carb. Res. 1979, 68:313-319.
Merriman and Bertram “Reversible inhibition by retinoids of 3-methylcholanthrene- induced neoplastic transformation in C3H10T1/2 cells.”Cancer Research1979, 39:1661-1666.
Hix Laura M.
Jackson Henry
Lockwood Samuel Fournier
Nadolski Geoff
O'Malley Sean
Hawaii Biotech, Inc.
Meyertons Eric B.
Solola Taofiq
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