Strong anion exchange composition

Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing

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C07F 710

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043225420

ABSTRACT:
A strong anion exchange composition useful in monophosphate nucleotide isomer separations is comprised of an inert porous particle having a silyl alkyl ammonium compound fixedly attached by a covalent silicon-oxygen-silicon bond to the surface thereof. A process for synthesizing the strong anion exchange composition in an aqueous solvent is disclosed together with methods for separation of monophosphate nucleotide isomers, highly phosphorylated nucleotides and aldopentose carbohydrates using a column packed with this strong anion exchange composition.

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Horvath et al., "Anal. Chem.", 39 (12), pp. 1422-1428 (1967).

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