Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Reexamination Certificate
2007-05-29
2007-05-29
Woodward, Michael P. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
C424S400000, C424S443000, C424S447000, C514S772000, C514S772300
Reexamination Certificate
active
09959420
ABSTRACT:
A stretch plaster comprising a support membrane having a thickness of 1 to 50 μm and a drug containing adhesive layer having a thickness of 3 to 400 μm, wherein(i) the support membrane comprising a copolymer of 0 to 90% by weight of vinyl acetate, 10 to 97% by weight of alkyl (meth)acrylate having 3 to 14 of a mean carbon number of alkyl group and 0 to 15% by weight of (meth)acrylic acid,(ii) the copolymer is cross-linked by polyvalent metal such as aluminum or a poly-functional chain compound, wherein the cross-linking ratio is 20% or more of the theoretical total number of carboxyl group of the copolymer when the polymer is cross-linked by the polyvalent metal such as aluminum, and is 1 to 10% expressed by copolymerized ratio of the poly-functional chain compound when the copolymer is cross-linked by poly-functional chain compound,(iii) the support membrane has 150 g or less of self adhesion shown by an adhesion between the support membranes and(iv) the support membrane has 70% or more of an elasticity recovery when it stretches 10% of itself.
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Kokubo, Takemasa, et al. “Diffusion of drug in acrylic-type pressure-sensitive adhesive matrices. I. Influence of physical property of the matrices on the drug diffusion”, Journal of Controlled Release 17 Sep. 1991, No. 1, Amsterdam, NL.
Hidaka Osafumi
Ohata Akiko
Silverman Eric E.
Sughrue & Mion, PLLC
Tiejin Limited
Woodward Michael P.
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