Stress protein compositions and methods for prevention and...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S252300, C435S325000

Reexamination Certificate

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08080388

ABSTRACT:
Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immunogenic polypeptide of the stress protein complex can be associated with a cancer or an infectious disease. Preferred immunogenic polypeptides include gp100, her2
eu ECD-PD, ICD andM. tuberculosisantigens. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease.

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