Stress protein compositions and methods for prevention and...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector

Reexamination Certificate

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C424S192100, C424S195110, C424S266100, C424S278100, C424S193100, C514S021800

Reexamination Certificate

active

07378096

ABSTRACT:
Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immunogenic polypeptide of the stress protein complex can be associated with a cancer or an infectious disease. Preferred immunogenic polypeptides include gp100, her2
eu ECD-PD, ICD andM. tuberculosisantigens. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease.

REFERENCES:
patent: 5747332 (1998-05-01), Wallen et al.
patent: 5830464 (1998-11-01), Srivastava
patent: 5858192 (1999-01-01), Becker et al.
patent: 5891432 (1999-04-01), Hoo
patent: 5961979 (1999-10-01), Srivastava
patent: 5981706 (1999-11-01), Wallen et al.
patent: 6017540 (2000-01-01), Srivastava et al.
patent: 6066716 (2000-05-01), Wallen et al.
patent: 6156302 (2000-12-01), Srivastava
patent: 6162436 (2000-12-01), Srivastava
patent: 6187312 (2001-02-01), Srivastava
patent: 6322790 (2001-11-01), Srivastava
patent: 6331299 (2001-12-01), Rothman et al.
patent: 6403095 (2002-06-01), Srivastava et al.
patent: 6451316 (2002-09-01), Srivastava
patent: WO 94/29459 (1994-12-01), None
patent: WO 95/24923 (1995-09-01), None
patent: WO 96/10411 (1996-04-01), None
patent: WO 97/06821 (1997-02-01), None
patent: WO97/06821 (1997-02-01), None
patent: WO 97/10000 (1997-03-01), None
patent: WO 97/10001 (1997-03-01), None
patent: WO 97/10002 (1997-03-01), None
patent: WO 97/26910 (1997-07-01), None
patent: WO 98/23735 (1998-04-01), None
patent: WO 98/34641 (1998-08-01), None
patent: WO 98/35705 (1998-08-01), None
patent: WO 99/07860 (1999-02-01), None
patent: WO 00/44899 (2000-08-01), None
Abstract of Wheeler (Salud p'ublica de M'exico, ( Jul.-Aug. 1997) 39 (4) 283-7).
Efferson et al (Anticancer Research, 2005, vol. 25, pp. 715-724.
Bachman et al (Journal of Immunology, 2005, vol. 175, pp. 4677-4685).
Oh et al, Journal of Biological Chemistry, 1997, vol. 272, pp. 31636-31640.
A.L. Rakhmilevich et al., “Effective Particle-mediated Vaccination Against Mouse Melanoma by Coadministration of Plasmid DNA Encoding Gp100 and Granulocyte-Macrophage Colony-Stimulating Factor,” Cancer Research, 2001, 7: 952-961.
C.I. Bargmann et al., “The neu oncogene encodes an epidermal growth factor receptor-related protein,” 1986, Nature, 319(16):226-230.
C.I. Bargmann et al., “Multiple Independent Activations of the neu Oncogene by a Point Mutation Altering the Transmembrane Domain of p185,” , 1986, Cell, 45:649-657.
N.E. Blachere et al., “Heat Shock Protein-Based Cancer Vaccines and Related Thoughts on Immunogenicity of Human Tumors,” Cancer Biology, 1995, vol. 6: 349-355.
N.E. Blachere et al., “Heat Shock Protein Vaccines Against Cancer,” Jnl. of Immunology, 1993, 14(4): 352-356.
W.R. Boorstein et al., “Molecular Evolution of the HSP70 Multigene Family,” 1994, J Mol Evol, 38:1-17.
C-H. Chen et al., “Enhancement of DNA Vaccine Potency by Linkage of Antigen Gene to an HSP70 Gene,” Cancer Research, 2000, vol. 60: 1035-1042.
X. Chen et al., “The 170 kCa glucose regulated stress protein is a large HSP70-HSP110-like protein of the endoplasmic reticulum,” XP-002060249, 1996, FEBS Letters, 380:68-72.
R.N. Coler, “Molecular Cloning and Immunologic Reactivity of a Novel Low Molecular Mass Antigen ofMycobacterium tuberculosis1,” 1998, J Immun, 161(5):2356-2364.
D.C. Dillon et al., “Molecular Characterization and Human T-Cell Responses to a Member of a NovelMycobacterium tuberculosis,” XP-002143391, 1999, Infection and Immunity, pp. 2941-2950.
M.L. Disis et al., “Generation of Immunity to the Her-2
euOncogenic Protein in Patients with Breast and Ovarian Cancer Using a Peptide-based Vaccine,” Clinical Cancer Research, 1999, vol. 5: 1289-1297.
T. Hatayama et al., “Association of HSP105 with HSC70 in High Molecular Mass Complexes in Mouse FM3A Cells,” 1998, Biochem and Biophys Res Comm, 248:395-401.
S. Janetzki et al., “Immunization of Cancer Patients with Autologous Cancer-Derived Heat Shock Protein gp96 Preparations: A Pilot Study,” International Jnl. of Cancer, 2000, vol. 88: 232-238.
S. Jindal, “Heat shock proteins: applications in health and disease,”1996, TB Tech, vol. 14, p. 5.
Z. Li, “Priming of T Cells by Heat Shock Protein-Peptide Complexes as the Basis of Tumor Vaccines,” Seminars in Immunology, 1997, vol. 9: 315-322.
M.H. Manjili et al., “Development of a Recombinant HSP110-HER-2
euVaccine Using the Chaperoning Properties of HSP110,” Cancer Research, 2002, vol. 62: 1737-1742.
M.H. Manjili et al., “Immunotherapy of Cancer Using Heat Shock Proteins,” Frontiers in Bioscience, 2002, vol. 7: d43-52.
A. Menoret et al., “Heat-Shock Protein-Based Anticancer Immunotherapy: An Idea Whose Time Has Come,” Seminars in Oncology, 1998, 25(6): 654-660.
Y. Moroi et al., “Induction of Cellular Immunity by Immunization with Novel Hybrid Peptides Complexed to Heat Shock Protein 70,” PNAS, 2000, 97(7): 3485-3490.
H. Oh et al., “The Chaperoning Activity of hsp110,” 1999, J of Biol Chem, 274(22):15712-15718.
H.J. Oh et al., “hsp110 Protects Heat-denatured Proteins and Confers Cellular Thermoresistance,” 1997, J Biol Chem, 272(5):31636-31640.
D.R. Palleros et al., “hsp70-Protein Complexes,” XP-002130137, 1994, 269(18):13107-13114.
D. Przepiorka et al., “Heat Shock Protein-Peptide Complexes as Immunotherapy for Human Cancer,” Molecular Medicine Today, 1998, 4(11): 478-484.
T. Shyy et al., “Effect of Growth State and Heat Shock on Nucleolar Localization of the 110,000-Da Heat Shock Protein in Mouse Embryp Fibroblasts1,” 1986, Cancer Research, 46:738-4745.
P.K. Srivastava, “Purification of Heat Shock Protein-Peptide Complexes for Use in Vaccination Against Cancers and Intracellular Pathogens,” Methods: A Companion to Methods in Enzymology, 1997, vol. 12: 165-171.
K. Suzue et al., “Heat shock fusion porteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway,” 1997, Proc Natl Acad Sci USA, 94:13146-13151.
Y. Tamura et al., “Immunotherapy of Tumors with Autologous Tumor-Derived Heat Shock Protein Preparations,” Science, 1997, vol. 278: 117-120.
H. Udono et al., “Generation of Cytotoxic T Lymphocytes by MHC Class I Ligands Fused to Heat Shock Cognate Protein 70,” International Immunology, 2001, 13(10): 1233-1242.
D.K. Vanaja et al., “Tumor Prevention and Antitumor Immunity with Heat Shock Protein 70 Induced by 15-Deoxy-Δ12,14-prostaglandin J2in Transgenic Adenocarcinoma of Mouse Prostate Cells,” Cancer Research, 2000, vol. 60: 4714-4718.
X-Y. Wang et al., “Characterization of Heat Shock Protein 110 and Glucose-Regulated Protein 170 as Cancer Vaccines and the Effect of Fever-Range Hyperthermia on Vaccine Activity,” Jnl. of Immunology, 2001, vol. 165, pp. 490-497.
S.P.K. Yedavelli et al., “Preventive and Therapeutic Effect of Tumor Derived Heat Shock Protein, gp96, in an Experimental Prostate Cancer Model,” International Jnl. of Molecular Medicine, 1999, 4(3): 243-248.
Moseley, P., “Stress proteins and the immune response”, Immunopharmacology, vol. 48, Jul. 2000, pp. 299-302.

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