Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1991-03-11
1995-11-28
Stone, Jacqueline
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 241, 435 691, 4351723, 4352523, 4352542, 43525421, 4353201, C12N 1531, C12N 1581
Patent
active
054709717
ABSTRACT:
Genes (and portions thereof) which are stress-inducible, e.g., by cold-shock which encode useful proteins. The proteins contribute to confer thermo-tolerance and/or contribute to confer low temperature tolerance to organisms, like eucaryotes or procaryotes. Typical genes encoding such proteins and homologous genes encoding proteins with equivalent properties are discussed. Nucleotide sequences encoding such proteins, recombinant replicable expression vehicles which comprise DNA constructs which encode such proteins and competent transformed organisms like eucaryotes are discussed. The production of valuable fermentation products and of biologically active proteins under conditions outside the normal or optimum physiological growth conditions are described.
REFERENCES:
Borkovich, K. A., et al. (1989), "hsp82 is an essential protein that is required in higher concentrations for growth . . . "etc., Mol. Cell. Biol., 9, 3919-3930.
Broach, J. R. et al., (1979), "Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene", Gene, 8, 121-133.
Caizergues-Ferrer, M. et al. (1989), "Nucleolin from Xenopus laevis: cDNA cloning and expression during development", Genes and Dev., 3, 324-333.
Craig, E. and Jacobsen, K. (1984), "Mutations of the heat inducible 70 kilodalton genes of yeast confer temperature sensitive growth", Cell, 38, 841-849.
Finely, D. et al. (1987), "The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses", Cell, 48, 1035-1046.
Goldstein et al. (1990), "Major cold shock protein of Escherichia coli", Proc. Natl. Acad. Sci. USA, 87, 283-287.
Jones, P. C. et al. (1987), "Induction of proteins in response to low temperature in Escherichia coli", J. Bacteriol., 169, 2092-2095.
Lindquist, S. and Craig, E. A. (1988), "The heat shock proteins", Annu. Rev. Genet., 22, 631-677.
Maniak, M. and Nellen, W. (1988), "A developmentally regulated membrane gene in Dictyostelium discoideum is also . . . "etc. Mol. Cell. Biol., 8, 153-159.
Marguet, D. and Lauquin, G. J. --M. (1986), "The yeast srp gene: positive modulation by glucose of its transcriptional . . . "etc. Biochem. Biophys. Res. Commum, 138, 297-303.
Marguet, D. et al. (1988), "Yeast gene SRP1 (Serine-rich protein) Intragenic repeat structure . . . "etc., J. Mol. Biol., 202, 455-470.
Muller-Taubenberger, A. et al. (1988), "Ubiquitin gene expression in Dictyostelium is induced by heat . . . "etc., J. Cell. Sci., 90, 51-58.
Neidhardt, F. C. et al. (1984), "The genetics and regulation of heat-shock proteins" Ann. Rev. Genet., 18, 295-329.
Nicolet, C. M. and Craig, E. A. (1989), "Isolation and characterization of STI1, a stress inducible gene . . . "etc., Mol. Cell. Biol., 9, 3638-3646.
Pelham, H. R. B. (1989), "Heat shock and the sorting of luminal ER proteins", EMBO J., 8, 3171-3176.
Petko, L. and Lindquist, S. (1986), "Hsp26 is not required for growth at high termperatures, nor for . . . "etc., Cell, 45, 885-894.
Sanchez, Y. and Lindquist, S. L. (1990), "Hsp104 required for induced thermotolerance", Science, 248, 1112-1115.
Schlesinger, M. J. (1990), "Heat shock proteins", J. Biol. Chem., 265, 12111-12114.
Srivastava, M. et al. (1990) "Genomic Organization and Chromosmal Localization of the Human Nucleolin Gene", JBC, 265, 14922-14931.
Werner-Washburne, M. et al. (1987), "Complex interactions among members of an essential sub-family of hsp70 . . . "etc., Mol. Cell. Biol., 7, 2568-2577.
Werner-Washburne, M. et al. (1989), "Yeast hsp70 RNA levels vary in response to the physiological . . . "etc., J. Bacteriol., 171, 2680-2688.
Marguet et al. J Mol. Biol. 202:455-470 (1988).
Inouye Masayori
Kondo Keiji
LeGuyader J.
Stone Jacqueline
The University of Medicine and Dentistry of New Jersey
LandOfFree
Stress-induced proteins, genes coding therefor, transformed cell does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Stress-induced proteins, genes coding therefor, transformed cell, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stress-induced proteins, genes coding therefor, transformed cell will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2014635