Streptomyces capable of producing neutral macrolide antibacteria

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435 76, 435886, 536 71, C12N 120, C12R 1465, C12P 1962, C07J 0000

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active

045433348

ABSTRACT:
An antibiotic complex, consisting of one major and two minor components, has been isolated from fermentation of a new Streptomyces culture. The components from the complex are three new macrolides which are active as antibacterial agents against certain gram-negative and gram-positive microorganisms.

REFERENCES:
patent: 3857937 (1974-12-01), Mancy et al.
patent: 4169140 (1979-09-01), Ohba et al.
Arnoux, et al., J. Am. Chem. Soc., 102, 3605 (1980).

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