Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-06-17
2008-06-17
Kam, Chih-Min (Department: 1656)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S076000, C435S252300, C435S471000
Reexamination Certificate
active
07388085
ABSTRACT:
The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures ofS. avermitilis. The present invention further relates to vectors, host cells, and mutant strains ofS. avermitilisin which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.
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Chen Yan
Gustafsson Claes
Kim Seran
Krebber Anke
Minshull Jeremy S.
Benson Gregg C.
Goddard Carl J.
Kam Chih-Min
Pfizer Inc
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