Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2003-08-06
2009-10-13
Mondesi, Robert B. (Department: 1645)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S007340
Reexamination Certificate
active
07601804
ABSTRACT:
The present invention relates to nucleic acid sequences encoding a 22.5 kDStreptococcus uberisprotein and to parts of such nucleic acid sequences that encode an immunogenic fragment of such proteins, and to DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof. The invention also relates to a 22.5 kDStreptococcus uberisprotein and immunogenic parts thereof encoded by such sequences. Furthermore, the present invention relates to vaccines comprising such nucleic acid sequences and parts thereof, DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof, proteins or immunogenic parts thereof and antibodies against such proteins or immunogenic parts thereof. Also, the invention relates to the use of said proteins in vaccines and for the manufacture of vaccines. Moreover, the invention relates to the use of said nucleic acid sequences, proteins or antibodies for diagnostic or vaccination purposes. Finally the invention relates to diagnostic kits comprising such a nucleic acid, protein or antibodies against such protein.
REFERENCES:
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Database Epofetch [Online!] (Jul. 01, 2002) Database accession No. ABN68115, XP002228319.
Database Epofetch [Online!] (Jul. 02, 2002) Database accession No. ABP27484, XP002228320.
Database Swiss-PROT [Online!] (Jun. 15, 2002) Database accession No. Q8P120, XP002228321.
Database EMBL [Online!] (Mar. 23, 2002) Database accession No. AE010036, XP002228322.
Tyler, J.W. et al.: “Immunization and immunotherapy for mastitis” Veterinary Clinics of North America (Nov. 1, 1993) V9, N3 p. 537-549, XP002095921.
Fontaine, M.C. et al.: “Immunisation of dairy cattle with recombinantStreptococcus uberisGapC . . . ” Vaccine Butterworth Scientific. (May 22, 2002) V20 N17-18, p. 2278-2286.
Leigh, J.A. “Streptococcus uberis: A Permanent Barrier to the Control of Bovine Mastitis?” Veterinary Journal, (May 1999) V157, N3, p. 225-238, XP009020371.
Vermeulen, A.N. “Progress in recombinant vaccine development against coccidiosis A reveiw . . . ” International J. Of Parasitology (Jul. 1998) V28, N7, P1121-1130, XP001024960.
Hensen Selma Marianne
Nuijten Petrus Johannes Maria
Blackstone William M.
Intervet International B.V.
Mondesi Robert B.
Shahnan-Shah Khatol
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