Streptococcus thermophilus strains and their use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

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435 32, 4352534, C12N 121, C12Q 102, C12Q 118

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active

056587481

ABSTRACT:
The invention relates to new Streptococcus thermophilus strains containing genes giving the bioluminescence property. The strains can be applied widely for analytical purposes, e.g. in the determination of bacteriophages and antibiotics, especially from liquid samples. The invention also relates to a test set containing a bioluminescent Streptococcus thermophilus strain, and to processes for the determination of bacteriophages or antibiotics from a liquid sample.

REFERENCES:
patent: 4929456 (1990-05-01), Mayra-Makinen
Ahmad et al.; "The Production of Bioluminescent Lactic Acid Bacteria Suitable for the Rapid Assessment of Strarter Culture Activity in Milk", Journal of Applied Bacteriology, vol. 70, pp. 113-120 1991.
Mercenier; "Molecular Genetics of Streptococcus thermophilus", FEMS Microbiology Reviews, vol. 87, pp. 61-78 1990.
Somkuti et al.; "Genetic Transformation of Streptococcus thermophilus by Electroporation", Biochimie, vol. 70, pp. 579-585 1988.
Ahmad et al, "Cloning of the lux genes into Lactobacillus casei and Streptococcus lactis: phosphate-dependent light production", Biochemical Society Transactions 16:1068 (1988).
Blissett et al, "In vivo bioluminescent determination of apparent K.sub.m 's for aldehyde in recombinant bacteria expressing luxA/B", Letters in Applied Microbiology 9:149-152 (1989).
Section 12. Gram-Positive Cocci, Berzey's Manual of Systematic Bacteriology, p. 1048 (1986).
Jacobs et al, "Highly bioluminescent Streptococcus thermophilus strain for the detection of dairy-relevant antibiotics in milk", Appl. Microbiol. Biotechnol. 44:405-412 (1995).

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