Streptococcus pneumoniae proteins and vaccines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S234100, C424S190100, C424S184100, C424S185100, C530S350000, C530S825000, C530S300000, C514S002600

Reexamination Certificate

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06887480

ABSTRACT:
The present invention relates to novel immunogenic polypeptides, and fragments thereof, and vaccines for the prevention and treatment of pneumococcal infection, especially byStreptococcus pneumoniae. The invention also relates to antibodies against the disclosed polypeptides, as well as vaccines containing said polypeptides and methods of disease prevention.

REFERENCES:
patent: 6582706 (2003-06-01), Johnson et al.
patent: WO 9818930 (1998-05-01), None
patent: WO 0006738 (2000-02-01), None
McGuinnes et al. Mol. Microbiol. 7: 505-514, 1993.*
McGuinnes et al. Lancet 337: 514-517, 1991.*
Houghten et al. Vaccines86, Cold Spring Harbor Laboratory, p. 21-25, 1986.*
Lazar et al. Mol. Cellular Biol. 8: 1247-1252, 1988.*
Burgess et al. J. Cell Biol. 111: 2129-2138, 1990.*
Bowie et al. Science 247: 1306-1310, 1990.*
Nayak et al., Infection and Immunity, 66:3744-3751 (1998).

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