Streptococcus pneumoniae capsular polysaccharide genes and flank

Details Streptococcus pneumoniae capsular polysaccharide genes and flank Streptococcus pneumoniae capsular polysaccharide genes and flank

1997-06-02

1999-09-07

Sisson, Bradley L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 237, C07H 2104, C07H 2102

Patent

active

059489006

ABSTRACT:
Disclosed is the identification, cloning and sequencing of flanking DNA regions common to all polysaccharide capsule types in Streptococcus pneumoniae. Also disclosed are particular type-specific genes and gene products that direct the formation of the Streptococcus pneumoniae serotype-specific polysaccharide capsule. Methods are provided for detecting Streptococcus pneumoniae. and for constructin gene cassettes that may be transferred as a unit during transformation and used to direct the expression of specific serotyes of Streptococcus pneumoniae capsules.

REFERENCES:
Sigma Molecular Biology a New Dimension 1989 p. 54.

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