Streptococcal immunoglobulin a binding protein encoded by emmL2.

Details Streptococcal immunoglobulin a binding protein encoded by emmL2. Streptococcal immunoglobulin a binding protein encoded by emmL2.

1991-12-24

1994-10-04

Draper, Garnette D.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

530350, 536 237, 4353201, 4352523, 43525233, C07K 1300, C12N 1531, C12N 121

Patent

active

053525884

ABSTRACT:
The subject invention concerns a novel polynucleotide sequence cloned from emm2.2 gene of a Group A streptococcus, Type II strain which codes for an IgA-binding protein, ML2.2. A process for producing the protein is given. The invention also concerns the protein in an immunoadsorbent and as a tracer for use in measuring and purifying IgA. Kits are given comprising the immunoadsorbent and the tracer form of the protein.

REFERENCES:
patent: 4757134 (1988-07-01), Blake et al.
patent: 5210183 (1993-05-01), Lindahl et al.
Bessen, D. E. et al. (1992) Infect. Immun. 60: 124-35.
Jeppson, H., et al. (1992) FEMS Microbiol. Lett. 92: 139-46.
Frithz, E., et al. (1989) Mol. Microbiol. 3: 1111-19.
Haanes, E. J., et al. (1989) J. Bacteriol. 171: 6397-6408.
Khandke, K. M., et al. (1988) J. Biol. Chem. 263: 5075-82.

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