Streptavidin-binding peptides and uses thereof

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07138253

ABSTRACT:
The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest.

REFERENCES:
patent: 5506121 (1996-04-01), Skerra et al.
patent: 5821047 (1998-10-01), Garrard et al.
patent: 6103493 (2000-08-01), Skerra et al.
patent: 6326157 (2001-12-01), Nolan et al.
patent: WO 98/31700 (1998-07-01), None
Bayer et al., “Postsecretory Modifications Of Streptavidin,”Biochem. J.259(2):369-376 (1989).
Caparon et al., “Analysis of Novel Streptavidin-Binding Peptides, Identified Using a Phage Display Library, Shows That Amino Acids External to a Perfectly Conserved Consensus Sequence and to the Presented Peptides Contribute to Binding,”Molecular Diversity1(4):241-246 (1995).
Cho et al., “Constructing High Complexity Synthetic Libraries of Long ORFs UsingIn VitroSelection,”J. Mol. Biol.297:309-319 (2000).
Clackson and Wells “In VitroSelection From Protein and Peptide Libraries,”TIBTECH. 12:173-184 (1994).
Devlin et al., “Random Peptide Libraries: A Source of Specific Protein Binding Molecules,”Science249(4967):404-406 (1990).
Giebel et al., “Screening of Cyclic Peptide Phage Libraries Identifies Ligands That Bind Streptavidin With High Affinities,”Biochemistry34(47):15430-15435 (1995).
Haeuptle et al., “Binding Sites for Lactogenic and Somatogenic Hormones From Rabbit Mammary Gland and Liver,”J. Biol. Chem.258(1):305-314 (1983).
Katz et al., “Topochemical Catalysis Achieved by Structure-Based Ligand Design,”J. Biol. Chem.270(52):31210-31218 (1995).
Katz and Cass, “In Crystals of Complexes of Streptavidin With Peptide Ligands Containing the HPQ Sequence the pKaof the Peptide Histidine is Less Than 3.0,”J. Biol. Chem.272(20):13220-13228 (1997).
Katz, B.A., “Structural and Mechanistic Determinants of Affinity and Specificity of Ligands Discovered or Engineered by Phage Display,”Annu. Rev. Biophys. Biomol. Struct.26:27-45 (1997).
Katz, B.A., “Streptavidin-Binding and -Dimerizing Ligands Discovered by Phage Display, Topochemistry, and Structure-Based Design,”Biomol. Eng.16(1-4):57-65 (1999).
Katz, B.A., “Binding to Protein Targets of Peptidic Leads Discovered by Phage Display: Crystal Structures of Streptavidin-Bound Linear and Cyclic Peptide Ligands Containing the HPQ Sequence,”Biochemistry34(47):15421-15429 (1995).
Kay et al., “An M13 Phage Library Displaying Random 38-Amino-Acid Peptides as a Source of Novel Sequences With Affinity to Selected Targets,”Gene128(1):59-65 (1993).
Keefe and Szostak, “ATP-Binding Proteins Selected From a Random-Sequence Polypeptide Library,”The Protein Society, Fourteenth Symposium, Program and Abstracts, 9(Suppl. 1):19 & 84 (No. 184-T), San Diego, CA (2000).
Lam et al., “A New Type of Synthetic Peptide Library for Identifying Ligand-Binding Activity,”Nature354(6348):82-84 (1991).
Liu et al., “Optimized Synthesis of RNA-Protein Fusions forIn VitroProtein Selection,”Methods Enzymol.318:268-293 (2000).
McCafferty et al., “Phage Antibodies: Filamentous Phage Displaying Antibody Variable Domains,”Nature348(6301):552-554 (1990).
McLafferty et al., “M13 Bacteriophage Displaying Disulfide-Constrained Microproteins,”Gene128(1):29-36 (1993).
Ostergaard et al., “Novel Avidin and Streptavidin Binding Sequences Found in Synthetic Peptide Libraries,”FEBS Letters362(3):306-308 (1995).
Roberts and Szostak, “RNA-Peptide Fusions for theIn VitroSelection of Peptides and Proteins,”Proc. Natl. Acad. Sci. USA94:12297-12302 (1997).
Roberts, R.W. “TotallyIn VitroProtein Selection Using mRNA-Protein Fusions and Ribosome Display,”Curr. Opin. Chem. Biol.3:268-273 (1999).
Schmidt and Skerra, “The Random Peptide Library-Assisted Engineering of a C-Terminal Affinity Peptide, Useful for the Detection and Purification of a Functional lg Fv Fragment,”Protein Eng6(1):109-122 (1993).
Schmidt et al., “Molecular Interaction Between the Strep-Tag Affinity Peptide and its Cognate Target, Streptavidin,”J. Mol. Biol.255:753-766 (1996).
Scott and Smith, “Searching for Peptide Ligands With an Epitope Library,”Science249(4967):386-390 (1990).
Szostak, J.W., “Evolution of Novel Proteins From Random-Sequence Libraries” 2000 (Abstract).
Weber et al., “Crystal Structure and Ligand-Binding Studies of a Screened Peptide Complexed With Streptavidin,”Biochemistry31(39):9350-9354 (1992).
Wilson et al., “The Use of mRNA Display to Select High-Affinity Protein-Binding Peptides,”PNAS98(7):3750-3755 (2001).
Zang et al., “Tight-Binding Streptavidin Ligands From a Cyclic Peptide Library,”Bioorg. Med. Chem. Lett.8(17):2327-2332 (1998).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Streptavidin-binding peptides and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Streptavidin-binding peptides and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Streptavidin-binding peptides and uses thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3652744

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.