Streptavidin-binding peptides and uses thereof

Details Streptavidin-binding peptides and uses thereof Streptavidin-binding peptides and uses thereof

2005-01-11

2005-01-11

Carlson, Karen Cochrane (Department: 1653)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

Reexamination Certificate

active

06841359

ABSTRACT:
The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest.

REFERENCES:
patent: 5506121 (1996-04-01), Skerra et al.
patent: 5821047 (1998-10-01), Garrard et al.
patent: 6103493 (2000-08-01), Skerra et al.
patent: 6326157 (2001-12-01), Nolan et al.
patent: WO 9831700 (1998-07-01), None
Katz BA. Binding to protein targets of peptidic leads discovered by phage display: crystal structures of streptavidin-bound linea and cyclic peptide ligands containing the HPQ sequence. Biochemistry. 1995 Nov. 28;34(47):15421-9.*
Bayer et al., “Postsecretory modifications of streptavidin,”Biochem. J. 259:369-376 (1989).
Cho et al., “Constructing high complexity synthetic libraries of long ORFs using in vitro selection,”J. Mol. Biol. 297:309-319 (2000).
Clackson et al., “In vitro selection from protein and peptide libraries,”TIBTECH. 12:173-184 (1994).
Devlin et al., “Random peptide libraries: A source of specific protein binding molecules,”Science249:404-406 (1991).
Giebel et al., “Screening of cyclic peptide phage libraries identifies ligands that bind streptavidin with high affinities,”Biochemistry34:15430-15435 (1995).
Haeuptle et al., “Binding sites for lactogenic and somatogenic hormones from rabbit mammary gland and liver,”J. Biol. Chem. 258:305-314 (1983).
Katz et al., “Topochemical catalysis achieved by structure-based ligand design,”J. Biol. Chem. 270:31210-31218 (1995).
Katz et al., “In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKaof the peptide histidine is less that 3.0,”J. Biol. Chem. 272:13220-13228 (1997).
Katz et al., “Structural and mechanistic determinants of affinity and specificity of ligands discovered or engineered by phage display,”Annu. Rev. Biophys. Biomol. Struct. 26:27-45 (1997).
Kay et al., “An M13 phage library displaying random 38-amino-acid peptides as a source of novel sequences with affinity to selected targets,”Gene. 128:59-65 (1993).
Lam et al., “A new type of synthetic peptide library for identifying ligand-binding activity,”Nature354:82-84 (1991).
Liu et al., “Optimized synthesis of RNA—protein fusions for in vitro protein selection,”Methods Enzymol., 318:268-293 (2000).
McLafferty et al., “M13 bacteriophage displaying disulfide-constrained microproteins,”Gene128:29-36 (1993).
McCafferty et al., “Phage antibodies: filamentous phage displaying antibody variable domains,”Nature348:552-554 (1990).
Ostergaard et al., “Novel avidin and streptavidin binding sequences found in synthetic peptide libraries,”Febs Letters362:306-308 (1995).
Roberts et al., “RNA—peptide fusions for the in vitro selection of peptides and proteins,”Proc. Natl. Acad. Sci. 94:12297-12302 (1997).
Roberts, “Totally in vitro protein selection using mRNA—protein fusions and ribosome display,”Curr. Opin. Chem. Biol. 3:268-273 (1999).
Schmidt et al., “The random peptide library-assisted engineering of a C-terminal affinity peptide, useful for the detection and purification of a functional Ig Fv fragment,”Protein Eng6:109-122 (1993).
Schmidt et al., “Molecular interaction between theStrep-tag affinity peptide and its cognate target,” J. Mol. Biol. 255:753-766 (1995).
Scott et al., “Searching for peptide ligands with an epitope library,”Science 249:386-390 (1990).
Weber et al., “Crystal structure and ligand-binding studies of a screened peptide complexed with streptavidin,”Biochemistry, 31:9350-9354 (1992).
Zang et al., “Tight-binding streptavidin ligands from a peptide library,”Bioorg. Med. Chem. Lett. 8:2327-2332 (1998).
Jack W. Szostak, “Evolution of Novel Proteins from Random-Sequence Libraries” 2000 (Abstract).
Szostak and Keefe, “ATP-Binding Proteins Selected from a Random-Sequence Polypeptide Library,” The Protein Society, Fourteenth Symposium, Program and Abstracts, vol. 9:Suppl. 1, San Diego, CA, pp. 19 and 84, 2000.
Caparon et al., “Analysis of Novel Streptavidin-Binding Peptides, Identified Using a Phage Display Library, Shows that Amino Acids External to a Perfectly Conserved Consensus Sequence and to the Presented Peptides Contribute to Binding,”Molecular Diversity1:241-246 (1995).
Katz, “Streptavidin-Binding and -Dimerizing Ligands Discovered by Phage Display, Topochemistry, and Structure-Based Design,”Biomolecular Engineering16:57-65 (1999).
Wilson et al., “The Use of mRNA Display to Select High-Affinity Protein-Binding Peptides,”PNAS98:3750-3755 (2001).

Affiliated with

Also associated with

Rating

Streptavidin-binding peptides and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Streptavidin-binding peptides and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Streptavidin-binding peptides and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3375012