Strepococcus pneumoniae gene sequence FtsH

Details Strepococcus pneumoniae gene sequence FtsH Strepococcus pneumoniae gene sequence FtsH

1997-12-08

2000-10-24

Myers, Carla J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 711, 435220, 4352523, 4353201, 435471, 435212, 536 232, 536 237, 536 2432, C07H 2104, C12N 120, C12N 1563, C12N 1500

Patent

active

061365572

ABSTRACT:
The invention provides isolated nucleic acid compounds encoding FtsH of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

REFERENCES:
patent: 5591839 (1997-01-01), Miller et al.
Toshifumi Tomoyasu, et al. "The Escherichia coli FtsH Protein Is a Prokaryotic Member of a Protein Family of Putative ATPase Involved in Membrane Functions, Cell Cycle Control, and Gene Expression." Journal of Bacteriology 175(5): 1344-1351 (Mar. 1993).
Simon Cutting, et al. "Spo VM, a Small Protein Essential to Development in Bacillus subtilis, Interacts with the ATP-Dependent Protease FtsH." Journal of Bacteriology 179(17) :5534-5542 (Sep. 1997).
Toshifumi Tomoyasu, et al. "Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor .sigma..sup.32." The EMBO Journal 14(11) :2551-2560 (1995).

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