Strand displacement assay and complex useful therefor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 2432, C12Q 168

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active

054459338

ABSTRACT:
The invention relates to an improvement in the strand displacement assay. Probes that are at least 20 nucleotide bases in length, but are no more than 40 bases in length, are used. These short probes permit detection and discrimination down to the order of a single base.

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patent: 4818680 (1989-04-01), Collins et al.
Sambrook et al., Molecular Cloning, Cold Spring Harbor Laboratory, New York, 1989, pp. 11.45-11.47, 11.55-11.57.
Heller et al. DNA Probes (Stockton Press, 1989), pp. 195-198.

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