Strains of phaffia rhodozyma containing high levels of astaxanth

Details Strains of phaffia rhodozyma containing high levels of astaxanth Strains of phaffia rhodozyma containing high levels of astaxanth

1997-03-28

1999-03-09

Prats, Francisco

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

4352551, 435 67, 424 9351, 426 62, 426540, 426805, 426807, C12N 116, C12P 2300, A23L 128, A61K 3572

Patent

active

058799273

ABSTRACT:
The present invention provides Phaffia rhodozyma strains having increased levels of astaxantin and a low percentage of 3-hydroxy-3',4'-didehydro-.beta.,.psi.-caroten-4-one (HDCO). Such strains are obtained by a combination of mutagenesis and selection. The invention further provides a method for obtaining such strains. The invention also provides astaxanthin obtained from a mutagenized strain of Phaffia rhodozyma characterized in that it contains a decreased relative amount of HDCO.

REFERENCES:
patent: 5182208 (1993-01-01), Johnson et al.
patent: 5648261 (1997-07-01), De Boer et al.
Phaff, H.J. et al., Proc. IV IFS 779-774 (1972).
Johnson, E.A. et al., Journal Gen. Micro 115:173-183 (1979).
An, Gill-Hwan et al., (1990) Antonie v. Leeuwenhoek 57:191-203.
Lewis, M.J. et al., Applied and Env. Micro. 56:2944-2945 (1990).
Cooper et al. J. Chem. Soc., Perkins Trans I, 1975, pp. 2195-2204.
An et al, Appl. Environ. Microbiol. 55(1):116-124, 1989.

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