Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1997-07-29
1999-08-17
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435115, 4352523, C12N 120, C12P 1308
Patent
active
059393076
ABSTRACT:
The present invention relates to novel strains of Escherichia coli and fermentation processes involving these microorganisms. More specifically, the present invention relates to genetically-modified Escherichia coli strains and the use thereof for the production of the amino acids, particularly members of the aspartate family of amino acids such as threonine. The present invention also relates to methods of preparing E. coli strains for use in the fermentative production of amino acids.
REFERENCES:
patent: 3375173 (1968-03-01), Nishimura et al.
patent: 3580810 (1971-05-01), Shiio et al.
patent: 3582471 (1971-06-01), Shiio et al.
patent: 3622453 (1971-11-01), Akeyama et al.
patent: 3647628 (1972-03-01), Nakayama et al.
patent: 3684653 (1972-08-01), Abe et al.
patent: 3684654 (1972-08-01), Nakayama et al.
patent: 3711375 (1973-01-01), Nakayama et al.
patent: 3732144 (1973-05-01), Nakayama et al.
patent: 4321325 (1982-03-01), Debabov et al.
patent: 4347318 (1982-08-01), Miwa et al.
patent: 4371615 (1983-02-01), Miwa et al.
patent: 4452890 (1984-06-01), Tsuchida et al.
patent: 4463094 (1984-07-01), Chibata et al.
patent: 4601983 (1986-07-01), Nakamori et al.
patent: 4757009 (1988-07-01), Sano et al.
patent: 4945058 (1990-07-01), Yanai et al.
patent: 4946781 (1990-08-01), Nakamori et al.
patent: 4980285 (1990-12-01), Sano et al.
patent: 4996147 (1991-02-01), Furukawa et al.
patent: 5017483 (1991-05-01), Furukawa et al.
patent: 5019503 (1991-05-01), Terasawa et al.
patent: 5077207 (1991-12-01), Shiio et al.
patent: 5087566 (1992-02-01), Takano et al.
patent: 5098835 (1992-03-01), Yamada et al.
patent: 5153123 (1992-10-01), Terasawa et al.
patent: 5164307 (1992-11-01), Yoshihara et al.
patent: 5175107 (1992-12-01), Debabov et al.
patent: 5188949 (1993-02-01), Tsuchida et al.
patent: 5217883 (1993-06-01), Anazawa et al.
patent: 5236831 (1993-08-01), Katsumata et al.
patent: 5264353 (1993-11-01), Yamada et al.
patent: 5342766 (1994-08-01), Yamada et al.
patent: 5376538 (1994-12-01), Kino et al.
patent: 5474918 (1995-12-01), Kino et al.
patent: 5631157 (1997-05-01), Debabov et al.
patent: 5705371 (1998-01-01), Debabov et al.
Saint Girons et al. (1985) Evidence for an internal promoter in the Escherichia coli threonine operator, Journal of Bacteriology 161(1): 461-462, Jan. 1985.
Gardner et al. (1975) Operator-promoter functions in the threonine operon of Escherichia coli, Journal of Bacteriology 124(1): 161-166, Oct. 1975.
Chan et al. (1993) Amplification of the trytophan operon gene in Escherichia coli chromosome to increase L-tryptophan biosynthesis, Applied Microbiology and Biotechnology 40(2/3): 301-305, Nov. 1993.
Little, S., et al., "Translational Coupling in the Threonine Operon of Escherichia coli K-12," J. Bacteriol. 171(6):3518-3522 (1989).
Mizukami, T., et al., "Improvement of the Stability of Recombinant Plasmids Carrying the Threonine Operon in an L-Threonine-hyperproducing Strain of Escherichia coli W," Agric. Biol. Chem. 50(4):1019-1027 (1986).
English language abstract of Taiwanese Patent Publication No. 258 753, Derwent World Patents Index Accession No. 95-392096.
International Search Report for International Application No. PCT/US97/13359.
Burr, B. et al., "Homoserine Kinase from Escherichia coli K12," Eur. J. Biochem. 62:519-526 (1976).
Cohen, G.N., "The Common Pathway to Lysine, Methionine, and Threonine," In: Amino Acids: Biosynthesis and Genetic Regulation, Herrmann, K.M. and Somerville, R.L., eds., Addison-Wesley Publ. Co., Reading, MA, publ., pp. 147-171 (1983).
Falcoz-Kelly, F. et al., "The Methionine-Repressible Homoserine Dehydrogenase and Aspartokinase Activities of Escherichia coli K 12," Euro. J. Biochem. 8:146-152 (1969).
Freundlich, M., "Multivalent Repression in the Biosynthesis of Threonine in Salmonella Typhimurium and Escherichia Coli," Biochem. Biophys. Res. Comm. 10(3):277-282 (1963).
Gardner, J.F., "Regulation of the threonine operon: Tandem threonine and isoleucine codons in the control region and translational control of transcription termination," Proc. Natl. Acad. Sci. USA 76(4):1706-1710 (1979).
Johnson, E.J. et al., "Threonyl-Transfer Ribonucleic Acid Synthetase and the Regulation of the Threonine Operon in Escherichia coli," J. Bacteriology 129(1):66-70 (1977).
Masuda, M. et al., "Improvement of Nitrogen Supply for L-Threonine Production by a Recombinant Strain of Serratia marcescens," Appl. Biochem. Biotech. 37:255-265 (1992).
Miwa, K. et al., "Construction of L-Threonine Overproducing Strains of Escherichia coli K-12 Using Recombinant DNA Techniques," Agric. Biol. Chem. 47(10):2329-2334 (1983).
Nass, G. et al., "Effect of the Antibiotic Borrelidin on the Regulation of Threonine Biosynthetic Enzymes in E. Coli," Biochem. Biophys. Res. Comm. 34(1):84-91 (1969).
Nass, G. and J. Thomale, "Alteration of Structure or Level of Threonyl-tRNA-Synthetase in Borrelidin Resistant Mutants of E. Coli," FEBS Letters 39(2):182-186 (1974).
Parsot, C. et al., "Nucleotide sequence of thrC and of the transcription termination region of the threonine operon in Escherichia coli K12," Nucl. Acids Res. 11(21):7331-7345 (1983).
Patte, J.-C. et al., "Regulation by Methionine of the Synthesis of a Third Aspartokinase and of a Second Homoserine Dehydrogenase in Escherichia Coli K.sub.12," Biochim. Biophys. Acta 136:245-257 (1967).
Shimizu, E. et al., "Culture Conditions for Improvement of L-Threonine Production Using a Genetically Self-cloned L-Threonine Hyperproducing Strain of Escherichia coli K-12," Biosci. Biotech. Biochem. 59(6):1095-1098 (Jun. 1995).
Theze, J. et al., "Mapping of the Structural Genes of the Three Aspartokinases and of the Two Homoserine Dehydrogenases of Escherichia coli K-12," J. Bacteriology 117(1):133-143 (1974).
Theze, J. and I. Saint-Girons, "Threonine Locus of Escherichia coli K-12: Genetic Structure and Evidence for an Operon," J. Bacteriology 118(3):990-998 (1974).
Truffa-Bachi, P. et al., "The Threonine-Sensitive Homoserine Dehydrogenase and Aspartokinase Activities of Escherichia coli K12," Euro. J. Biochem. 5:73-80 (1968).
English Language abstract of JP 53-101591, Derwent Accession No. 78-73642A/197841.
Binder Thomas P.
Bradshaw Jill S.
Hanke Paul D.
Liaw Hungming James
Swisher Stacia L.
Stole Einar
The Archer-Daniels-Midland Company
Wax Robert A.
LandOfFree
Strains of Escherichia coli, methods of preparing the same and u does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Strains of Escherichia coli, methods of preparing the same and u, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Strains of Escherichia coli, methods of preparing the same and u will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-314479