Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1981-12-30
1984-01-31
Naff, David M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
424181, 435118, 435123, 435253, 435886, C12P 1718, C12P 1702, C12R 1465, C12N 120
Patent
active
044290420
ABSTRACT:
Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the prevention and cure of parasitic infections.
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patent: 4160861 (1979-07-01), Cole et al.
patent: 4161583 (1979-07-01), Wilson et al.
patent: 4285963 (1981-08-01), Arison et al.
Mishima et al., Structures of Milbemycin B1, B2 and B3, Tetrahedron Letters, vol. 10, 1975 (pp. 711-714).
Albers-Schonberg George
Burg Richard W.
Miller Thomas W.
Ormond Robert E.
Wallick Hyman
Merck & Co. , Inc.
Naff David M.
Rose David L.
Westlake Harry E.
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