Storage stability of aqueous dispersions of spherules

Compositions – Preservative agents – Anti-corrosion

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424 36, 424 59, 424 62, 424 65, 424 85, 424 94, 424280, 424317, B01J 1302, A01N 2528, A61K 950, A61K 964

Patent

active

042474116

ABSTRACT:
Aqueous dispersions of spherules in the form of organized molecular layers of lipids, between which is encapsulated an aqueous phase containing at least one active substance are rendered more storage-stable by lyophilization. They can readily be reconstituted by re-hydration.

REFERENCES:
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patent: 3041289 (1962-06-01), Katchen et al.
patent: 3173878 (1965-03-01), Reyes
patent: 3336155 (1967-08-01), Rowe
patent: 3630920 (1971-12-01), Freifeld et al.
patent: 3932657 (1976-01-01), Rahman
patent: 3957971 (1976-05-01), Oleniacz
patent: 4016100 (1977-04-01), Suzuki et al.
Chem. Abstracts, vol. 85, No. 2, p. 258, Jul. 26, 1976.

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