Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Blood gas standard or control
Patent
1992-05-22
1993-05-18
Housel, James C.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Blood gas standard or control
436 18, 436127, 436133, 73 1R, 73 2321, 204403, G01N 3100, G01C 1738, A61B 505
Patent
active
052120929
ABSTRACT:
The solution for storage and calibration of an intravascular blood sensor is an aqueous solution of from 10-35 mM of a first buffer component of bicarbonate, and at least one additional buffer component selected to maintain the pH of the solution substantially at or slightly below a neutral pH, and preferably below approximately pH 8. The first and additional buffering components preferably are selected to act in two separate pH regions with substantially no overlap of the buffering capacity of the different buffering components, and the concentration of the first buffer component in the solution is selected to permit a two point calibration of the intravascular multiparameter blood sensor by carbon dioxide and oxygen gas tonometry.
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Otto S. Wolfbeis and Leonie J. Weis, Fiber-Optic Fluorosensor for Oxygen and Carbon Dioxide, 1988, pp. 2028-2030, vol. 60, Anal. Chem.
Hui Henry K.
Jackson Jeffrey T.
Bhat N.
Housel James C.
Puritan-Bennett Corporation
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