Optics: measuring and testing – With sample preparation
Reexamination Certificate
2011-08-02
2011-08-02
Punnoose, Roy (Department: 2886)
Optics: measuring and testing
With sample preparation
Reexamination Certificate
active
07990524
ABSTRACT:
A rapid-sampling stochastic scanning multiphoton multifocal microscopy (SS-MMM) fluorescence imaging technique enables multiparticle tracking at rates upwards of 1,000 times greater than conventional single point raster scanning. Stochastic scanning of a diffractive optical element may generate a 10×10 hexagonal array of foci with a white noise driven galvanometer to yield a scan pattern that is random yet space-filling. SS-MMM may create a more uniformly sampled image with fewer spatio-temporal artifacts than obtained by conventional or multibeam raster scanning.
REFERENCES:
patent: 5677093 (1997-10-01), Delabastita et al.
patent: 5734498 (1998-03-01), Krasieva et al.
patent: 5858589 (1999-01-01), Govaert et al.
patent: 6028306 (2000-02-01), Hayashi
patent: 6128077 (2000-10-01), Jovin et al.
patent: 6208411 (2001-03-01), Vaez-Iravani
patent: 6278521 (2001-08-01), Jablonski et al.
patent: 6399935 (2002-06-01), Jovin et al.
patent: 6766184 (2004-07-01), Utzinger et al.
patent: 6864989 (2005-03-01), Storz et al.
patent: 7339148 (2008-03-01), Kawano et al.
patent: 7492535 (2009-02-01), Descour et al.
patent: 7698000 (2010-04-01), Silberberg et al.
patent: 2002/0043618 (2002-04-01), Storz et al.
patent: 2008/0130093 (2008-06-01), Silberberg et al.
Andresen, et al. “Time-multiplexed multifocal multiphoton microscope,” Opt. Lett. 26:75-77 (2001).
Bewersdorf, et al. “Multifocal multiphoton microscopy,” Opt. Lett. 23:655-657 (1998).
Crocker, et al. “Methods of digital video microscopy for colloidal studies,” J. Coll. Inter. Sci. 179:298-310 (1996).
Diaspro,Confocal and two-photon microscopy(Wiley, New York, 2002).
Egner, et al. “Time multiplexing and parallelization in multifocal multiphoton microscopy,” J. Opt. Soc. Am. A 17, 1192-1201 (2000).
Fittinghoff, et al. “Time-decorrelated multifocal array for multiphoton microscopy and micro-maching,” Opt. Lett. 25:1213-1215 (2000).
Jin, et al. “Correlating second harmonic optical responses of single Ag nanoparticles with morphology,” J. Amer. Chem. Soc. 127:12482-12483 2005.
Kim, et al. “High-speed, two-photon scanning microscope,” Appl. Opt. 38:6004-6009 (1999).
Sacconi, et al. “Multiphoton multifocal microscopy exploiting a diffractive optical element,” Opt. Lett. 28:1918-1920 (2003).
Toussaint, Jr., et al. “Generation of optical vector beams using a diffractive optical element interferometer,” Opt. Lett. 30:2846-2848 (2005).
Jureller, “Nonlinear and correlation microscopies for dynamics and function in heterogeneous systems,” Ph.D. Dissertation, The University of Chicago (2006).
Dank, et al. “Two-Photon Laser Scanning Fluorescence Microscopy,” Science 248:73-76 (1990).
Digman, et al. “Measuring Fast Dynamics in Solutions and Cells with a Laser Scanning Microscope,” Biophysical Journal 89:1317-1327 (2005).
Jiang “Non-scanning Fluorescence Confocal Microscopy using Laser Speckle Illumination,” The University of Nottingham, pp. 1-141 (2005).
Jureiler, et al, “Stochastic scanning multiphoton multifocal microscopy,” Optics Express 14(8):3406-3414 (Apr. 17, 2006).
Levi, et al. “3-D Particle Tracking in a Two-Photon Microscope: Application to the Study of Molecular Dynamics in Cells,” Biophysical Journal 88:2919-2928 (2005).
Oron, at al. “Scanningless depth-resolved microscopy,” Optics Express 13(5):1468-1476 (2005).
Jureller Justin E.
Kim Hee Y.
Scherer Norbert F.
Marshall & Gerstein & Borun LLP
Punnoose Roy
The University of Chicago
LandOfFree
Stochastic scanning apparatus using multiphoton multifocal... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Stochastic scanning apparatus using multiphoton multifocal..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stochastic scanning apparatus using multiphoton multifocal... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2685121