Stimulus responsive affinity chromatographic material and...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

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C530S413000, C530S395000

Reexamination Certificate

active

07012136

ABSTRACT:
A separation material characterized by supporting, in its surface, a linear or crosslinked stimulus responsive polymer to which a substance A having specific affinity for a target substance and a low-molecular substance B having specific affinity for the substance A have been bonded. Such a separation material can increase the recovery of a target substance to be purified and do not require desalting and hapten sugar-eliminating operations and, in addition, have high productivity.

REFERENCES:
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patent: 2000-140632 (2000-05-01), None
patent: WO00/67901 (2000-11-01), None
Kanazawa et al., Temprature-responsive chromatography, 1998, Trends in Analytical Chemistry, vol. 17, No. 7 pp. 435-440.
Yamanaka et al., Development of Temprature Regulated Elution System for Lectin Affinity Chromatography, 2000, Chromatography, vol. 21, No. 4 pp. 324-325.

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