Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-10-23
2007-10-23
Swope, Sheridan (Department: 1652)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S194000, C435S320100, C435S252300, C435S252330, C435S325000
Reexamination Certificate
active
10338462
ABSTRACT:
Compositions and methods are provided for treating NF-κB-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-κB cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-κB activation.
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Barbosa Miguel
Li Jian Wu
Mercurio Frank
Murray Brion W.
Zhu Hengyi
Jones Day
Signal Pharmaceuticals
Swope Sheridan
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