Stimulation of hair growth by peptide copper complexes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 18, 514 19, 530304, A61K 3804

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active

055389457

ABSTRACT:
Peptide-copper complexes are disclosed which stimulate the growth of hair on warm-blooded animals. In one aspect of this invention, the peptide-copper complexes are dipeptides or tripeptides chelated to copper at a molar ratio ranging from about 1:1 to 3:1, with the second position of the peptide from the amino terminus being histidine, arginine or a derivative thereof. The peptide-copper complexes may be formulated for administration by, for example, topical application or injection. Any affliction associate with hair loss, including hair loss associated with both androgenetic and secondary alopecia, may be treated with the peptide-copper complexes of this invention.

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Uno, H. et al. Macaque and Rodent Models for the Screening of Drugs for Stimulating Hair Growth. Journal of Cutaneous Aging and Cosmetic Dermatology 1, 193-204 (1990).
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