Stimulation of endothelial cell growth

Details Stimulation of endothelial cell growth Stimulation of endothelial cell growth

1987-08-21

1991-04-16

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

43524021, 43524023, 43524031, 530324, 530380, 514 12, 514 21, C12N 500, A61K 3700, C07K 700

Patent

active

050081969

ABSTRACT:
A method of stimulating endothelial cell growth is provided which comprises subjecting said cells to a growth stimulating amount of a highly purified vascular permeability factor having the following characteristics:

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Senger et al., Science, 219, 983-985, (1983).
Folkman and Klagsbrun, Science, 235, 442-447, (1987).
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Dvorak, N. Engl. J. Med., 315, 1650-1659, (1986).
Kadish et al., Tissue & Cell, 11, 99, (1979).
Dvorak et al., J. Natl. Cancer Inst., 62, 1459-1472, (1979).
Senger et al., Cancer Res., 46, 5629-5632, (1986).
Lobb et al., Int. J. Cancer, 36, 473-478, (1985).

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