Stimulation of antigen production by Bordetella pertussis

Details Stimulation of antigen production by Bordetella pertussis Stimulation of antigen production by Bordetella pertussis

1983-09-15

1985-11-05

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435 70, 435243, 435244, 435255, 424 88, 424 92, 260112R, C12N 138, C12N 110, C12N 100, A61K 3902, A61K 3910, C12P 2100, C12P 2102

Patent

active

045514291

ABSTRACT:
A method for the elaboration of large quantities of Bordetella pertussis protective antigens useful in the production of acellular vaccines for prevention of whooping cough.

REFERENCES:
patent: 2240969 (1941-05-01), Voigt et al.
patent: 4455297 (1984-06-01), Syukuda et al.
Imaizumi et al., Abstracts of the 1982 ICAAC, p. 109, Abstract 251, "A New Shaking Culture Method for the Production of Pertussis Component Vaccine . . . ".
Arai et al., Biochimica et Biophysica Acta, Vo. 444, (1976), pp. 765-782, "Separation and Characterization of Two Distinct Hemagglutinins Contained in Purified Leukocytosis-Promoting Factor from JJ Bordetella pertussis.
Botre et al., Chem. Abst., vol. 62, 1965, p. 966, "Influence of Polymers on Penicillium chrysogenum Fermentation".
Hewlett et al., J. of Bact., vol. 127(2), Aug. 1976, pp. 890-898, "Soluble Adenylate Cyclase from the Culture Medium of Bordetella pertussis: Purification and Characterization".
Cohen et al., Amer. J. Public Health, Apr. 1946, pp. 371-376, vol. 36, "Pertussis Vaccine Prepared with Phase-I Cultures Grown in Fluid Medium".
Botre et al., "Influenza di Alcuni Polimeri Nella Fermentazione del `Penicillium Chrysogenum`, Farmaco. Ed. Pract. 19, 507ff, (1964), (translated portions only).

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