Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2007-12-25
2007-12-25
Badio, Barbara P. (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C540S107000, C540S108000, C540S113000, C514S176000, C435S320100, C424S450000
Reexamination Certificate
active
10468652
ABSTRACT:
Disclosed is a sterol derivative having a pKa value of 3.5-8 according to the general formula cation-spacer 2-Y-spacer 1-X-sterol, wherein Y and X represent bonding groups. The invention also relates to liposomes containing said sterol derivatives.
REFERENCES:
patent: 4788182 (1988-11-01), Baschang et al.
patent: 4891208 (1990-01-01), Janoff et al.
patent: 5365487 (1994-11-01), Patel et al.
patent: 5888821 (1999-03-01), Reszka
patent: 2003/0157181 (2003-08-01), Panzner et al.
patent: 0169812 (1986-01-01), None
patent: 02331417 (1990-11-01), None
patent: WO 93/05162 (1993-03-01), None
patent: WO 96/20208 (1996-07-01), None
patent: WO 97/39019 (1997-04-01), None
patent: WO 97/31935 (1997-09-01), None
patent: WO 97/454442 (1997-12-01), None
patent: WO 00/28972 (2000-03-01), None
patent: WO 01/64330 (2001-03-01), None
patent: WO 02/00680 (2002-01-01), None
Budker et al:,PH-Sensitive, Cationic Liposomes: A New Synthetic Virus-Like Vector, Bio/Technology, Nature Publishing Co., New York, NY, US; vol. 14, Jun. 1996.
Tang F. et al.;Introduction of a Disulfide Bond Into a Cationic Lipid Enhances Transgene Expression of Plasmid DNA; Biochemical and Biophysical Research Communications, Academic Press Inc., Orlando, FL, US; vol. 242, No. 1; Jan. 6, 1998.
Fichert T et al;Synthesis and Transfection Properties of Novel Non-Toxic Monocationic Lipids. Variation of Lipid Anchor, Spacer and Head Group Structure, Bioorganic & Medicinal Chemistry Letters, Oxford, GB; vol. 10, No. 8, Apr. 2000.
Tachibana et al,Intracellular Regulation of Macromolecules Using pH-Sensitive Liposomes and Nuclear Localization Signal: Qualitative and Quantitative Evaluation of Intracellular Trafficking, Biochemical and Biophysical Research Communications 251, 538-544 (1998) Article No. TC989460.
Handbook of Chemistry and Physics, 73. Band, S. 8-37 ff date needed.
T.V. Konstantinova et al.,Synthesis of Cholesterol-Containing Cationic Amphiphiles with Heterocyclic Bases, Russian Journal of Bioorganic Chemistry, XP002207246.
Behrens Anja
Endert Gerold
Fankhänel Stefan
Panzner Steffen
Akerman & Senterfitt
Badio Barbara P.
Novosom AG
Pendorf Stephan
LandOfFree
Sterol derivatives, liposomes comprising sterol derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sterol derivatives, liposomes comprising sterol derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sterol derivatives, liposomes comprising sterol derivatives... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3832836