Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1995-06-07
1998-04-28
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514178, A61K 3156, C07J 900, C07J 1100, C07J 1300
Patent
active
057444625
ABSTRACT:
Compounds of the formulae: ##STR1## useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agent.
REFERENCES:
patent: 2833793 (1958-05-01), Dodson et al.
patent: 2911418 (1959-11-01), Johns et al.
patent: 3018298 (1962-01-01), Klimstra et al.
patent: 3148198 (1964-09-01), Goldcamp
patent: 3166578 (1965-01-01), Klimstra et al.
patent: 3357888 (1967-12-01), Campbell et al.
patent: 3391166 (1968-07-01), Klimstra
patent: 3471480 (1969-10-01), Fritsch et al.
patent: 3471526 (1969-10-01), Klimstra
patent: 3580937 (1971-05-01), Campbell et al.
patent: 3976691 (1976-08-01), Middleton et al.
patent: 4518595 (1985-05-01), Coleman et al.
patent: 4628052 (1986-12-01), Peat
patent: 4666898 (1987-05-01), Coleman et al.
patent: 4897390 (1990-01-01), Ruhe
patent: 4898694 (1990-02-01), Schwartz et al.
patent: 5001119 (1991-03-01), Schwartz et al.
patent: 5028631 (1991-07-01), Schwartz et al.
Rao et al. Cancer Research (51), 4528-4534, Sep. 1, 1991.
Schwartz et al. Carcinogenesis, vol. 10, No. 10, 1809-1813, 1989.
Ratko et al. Cancer Research (51), 481-486, Jan. 15, 1991.
Goodman and Gilman's "The Pharmacological Basis of Therapeutics", seventh edition, pp. 1243-1245, 1986.
Schwartz, Nutr Cancer, 3, 46-53 (1981).
Fels Ann. Report 1979-1980 pp. 32-33.
Pashko, Chem. Abs. 101315K (1984).
Schwartz, et al., Chem Abs. 103, 123791m (1985).
Robinson, et al., J. Org. Chem. 28, 975-980 (1963).
Hanson, et al. Perkin Transactions I, 499-501 (1977).
Goldman, et al., Biochimica and Biophysics Acta, 233-249 (1973).
Pashko, et al., Carcinogenesis, 2, 717-721 (1981).
Abou-Gharbia et al., Journal of Pharmaceutical Sciences, 70, 1154 (1981).
Raineri and Levy, Biochemistry 9, 2233-2243 (1970).
Pelc, et al., Collection Czechoslov. Chem. Comm., 31, 1064 (1966).
Klimstra, et al., Journal of Med. Chem. 9, 924 (1966).
Bridgeman, et al., J. Chem. Soc., C, 250 (1970).
Mailloux, et al., Bulletin de la Societe Chemique de France, 617 (1969).
Catsoulacos, Chemical Abstracts 67, 54331K (1967).
Catsoulacos, et al., J. Org. Chem., 32, 3723-3724 (1967).
Sheppard, et al., J.C.S. Perkins I, 2551 (1977).
Crabb, et al., J.C.S. Perkins I, 1041 (1981).
Bird, Chemical Abstracts 92, 213616v (1980).
Geoffrey, et al., J.C.S. Perkins I, 750 (1980).
Kirk, et al., J.C.S. Perkins I, 762 (1976).
Evans, Chemical Abstracts 79, 42729 (1973).
Denny, et al., J.C.S. Perkins I, 486 (1972).
Chemical Abstracts 89, 105865g (1978).
Djerassi, Carl, "Steroid Reactions", p. 199 (1963).
"Chemical Abstracts 42", 11647f-11648g (1965).
Chemical Abstracts 85: 5945b (1976).
Numazawa, et al., Steroids 32, 514-527 (1978).
Pashko, et al., Carcinogenesis 5, #4, 463-466 (1984).
Pashko, et al., Carcinogenesis 12, 2189 (1696).
Merck Index 1976, p. 376.
Chemical Abstracts 89, 10586b (1978).
Marguet, Memoires Present A+ La Sciete Chemique pp. 1822-1831 (1978).
Shoppe, et al., J.C.S. (C) 2767 (1969).
Bird, et al., Journal of Chemical Society, 1979, pp. 65-66.
Jones, et al., Journal of Chemical Society, Perkin Transactions I, 22, 1975, 2308-2312.
Wolf et al., J. Org. Chem. 41, No. 7, 1976, pp. 1254-1255.
Combe, e al., J.C.S., Series C, pp. 2300-2305 (1971).
Jones, et al., J.C.S., Series C, 2421-2426 (1970).
Labler, et al., Collection Czechoslov. Chem. Comm., 33, 2226-2237 (1967).
Chemical Abstracts 63, 11647-11648 (1965).
Ramseyer, et al., Steroids, 3347-3365 (1967).
Johnston, et al., J.C.S., Series C, 1847-1856 (1966).
Browne et al., J.C.S., Perkin Transactions I, pp. 1493-1499 (1973).
Chemical Abstracts 85, 5945b (1976).
Gerhards, et al., Arzneimittel Forschunq 16, 458-463 (1968).
Lewbart Marvin Louis
Schwartz Arthur G.
Berch Mark L.
Kifle Bruck
Research Corporation Technologies Inc.
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